First Meeting
The first meeting of COST Action is organized in Lisbon on 26 January 2023.
The meeting type is hybrid; thus, everyone can partecipate at least by remote access.
COST ACTION CA21145
European Network for diagnosis and treatment of antibiotic-resistant bacterial infections (EURESTOP)
Lisbon, 26-27 January 2023
COST action CA21145, 1st Meeting
Research Center for Biosciences & Health Technologies (CBIOS)
Universidade Lusófona de Humanidades e Tecnologias Lisbon, Portugal
Location and dates: Lisbon, Portugal 26-27 January 2023
Venue: CBIOS, Universidade Lusófona de Humanidades e Tecnologias, Campo Grande 376, 1749-024
Remote access: https://videoconf-colibri.zoom.us/j/91185124432
Scientific Committee:
Mattia Mori (Italy) – Action Chair
Patricia Rijo (Portugal) – Vice Chair
Cristina Nativi (Italy) – Science Communication coordinator
Priyanka Sahariah (Iceland) – Grant Awarding coordinator
Dana Reichmann (Israel) – WG1 Leader
Younes Smani (Spain) – WG2 Leader
Carole Devaux (Luxembourg) – WG3 Leader
Local Organizing Committee:
Patrícia Rijo (Local Organizer)
Vera Isca (Portugal)
Márcia Filipe (Portugal)
Gabrielle Bangay (Portugal)
Daniel Santos (Portugal)
Ana Mourato (Portugal)
Andreia Rosatella (Portugal)
Management: Carolina Altilia – COST Action CA21145 – info@eurestop.eu
CA21145 SUMMARY
The emergence and spread of drug-resistant bacteria is an important health and socioeconomic threat with global dimensions, which is developing towards an emergency/pandemic crisis. No drugs are available to address the disease, and diagnostic tools are poorly effective. This negatively impacts the treatment and survival of critically ill patients. As such, drug-resistant bacteria may spread outside hospital settings, representing a critical risk for the global population. Current research in this field is highly fragmented and mostly monodisciplinary, thus limiting the development of innovative diagnostic and therapeutic solutions.
This COST Action will bring together industrial and academic European scientists with different skills and expertise in a multidisciplinary and concerted initiative. The Action will combine disciplines such as chemistry, physics, bioinformatics, genetics, biology, immunology, and medicine in understanding the genetic and molecular bases of bacterial drug resistance, developing innovative diagnostic tools, and delivering lead/pre-clinical candidates, antibody-based therapies, and clinical-ready repurposed drugs towards the personalized treatment of drug-resistant bacterial infections. The further challenge of the Action is to enhance networking among European scientists and to increase the competitiveness of European research by promoting the exploitation of translational research outcomes, e.g., by the creation of novel SMEs. Finally, by knowledge creation and sharing, the Action will train a new generation of young scientists skilled in the multiple aspects related to bacterial drug resistance. Career development of Young Researchers and Innovators and research impulses in Inclusiveness Target Countries (ITC) will be considered as a priority in the Action.
Program
26th January 2023
https://videoconf-colibri.zoom.us/j/91185124432
8:15 – 9:00 Registration of participants
9:00 – 9:15 Opening:
Mattia Mori – CA21145 Chair
L. Monteiro Rodrigues – CBIOS Director
Patrícia Rijo – Local organizer
Session 1 | Chairman: CRISTINA NATIVI (Italy)
9:15 -10:00 Invited Expert: Marco Maria D’Andrea Università di Roma “Tor Vergata”, Italy
Antibiotics and antibiotic resistance: lessons from the past to guide future actions
10:00 -10:15 Magne Sydnes University of Stavanger, Norway
Post-use photodecomposition – quicker removal of antimicrobial agents from the environment
10:15 -10:30 Abidelfatah Nasser Beitberl College of Education, Israel
Environmental Dissemination of antibiotic resistant bacteria (ARB) and genes (ARG) by the discharge of Wastewater Effluents
10:30 – 10:45 Vladimír Křen Czech Academy of Sciences, Czech Republic
Flavonolignans from silymarin as MDR inhibitors
10:45 – 11:15 Coffee break
Session 2 | Chairman: DANA REICHMANN (Israel)
11:15 – 11:30 Simone Carradori University of Chieti-Pescara, Italy
Pseudomonas aeruginosa carbonic anhydrase inhibitors as innovative antibacterial agents to combat antibiotic resistance: ciprofloxacin derivatives
11:30 – 11:45 A. Basak Kayitmazer Bogazici University, Turkey
Soft Matter for Understanding and Treating Antibiotic-Resistant Bacterial Infections
11:45 – 12:00 Ivanka Tsakovska Bulgarian Academy of Sciences, Bulgaria
Development and application of in silico approaches to predict pharmacologial/toxic effects of bioactive compounds
12:00 – 12:15 Nuno R. Candeias University of Aveiro, Portugal
Phenolic Mannich bases as antibacterials agents for Staphylococcus aureus
12:15 – 12:30 Yves Mèly University of Strasbourg, France
Developing new strategies to image, target and kill gram negative bacteria
12:30 – 12:45 Lul Raka National Institute of Public Health of Kosova, Kosovo
Addressing antimicrobial resistance in Kosova
12:45 – 14:30 Lunch break (& group picture at 14:20 in front of the Auditorium entrance)
Session 3 | Chairman: CAROLE DEVAUX (Luxembourg)
14:30 – 14:45 Vera M. S. Isca Universidade Lusófona, Portugal
Antimicrobial screening of Plectranthus extracts for applications against antibiotic resistant bacterial infections
14:45 – 15:00 Ana Martins Biological Research Centre, Hungary
Laboratory evolution as a key tool in antimicrobial development
15:00 – 15:15 Ismail Ocsoy Erciyes University, Turkey
Development of natural and synthetic anthocyanin incorporated phenotypic tests for colorimetric, fast and sensitive detection of antibiotic resistance bacteria in clinic
15:15 – 15:30 Constantinos Athanassopoulos University of Patras, Greece
Natural product antibacterial agents and rediscovery of old antibiotics
15:30 – 15:45 Michail Christodoulou University of Milan, Italy
4-(1,2,2-triphenylvinyl)aniline as self-assembling inducer
15:45 – 16:15 Coffee break
16:15 – 16:30 Matthew Borg COST Association
Q&A – reimbursement rules and eligible expenses
16:15 – 17.15 Working Groups Meeting
WG1 – Room D.1.11
Remote connection: https://videoconf-colibri.zoom.us/j/99354119338 Meeting ID: 99354119338
WG2 – Room D.1.13
Remote connection: https://videoconf-colibri.zoom.us/j/96883839475 Meeting ID: 968 8383 9475
WG3 –conference auditorium
Remote connection: https://videoconf-colibri.zoom.us/j/91185124432 (same as the main conference)
17:15 – 18:45 MC Meeting – ONLY FOR MC MEMBERS
Conference auditorium
Social dinner – Chimarrão Campo Grande – 19:30-22:00 (https://chimarrao.pt/)
27th January 2023
https://videoconf-colibri.zoom.us/j/91185124432
Session 4 | Chairman: PATRICIA RIJO (Portugal)
9:15 – 10:00 Invited Expert: Artur Silva University of Aveiro, Portugal
Biologically active oxygen and nitrogen heterocyclic compounds from cycloaddition and conjugate addition reactions on chromones
10:00 – 10:15 Tomislav Mestrovic University North, University centre Varaždin, Croatia
Estimating the burden of bacterial antimicrobial resistance in Europe and beyond: a systematic data- driven approach for research and implementation priority setting
10:15 – 10:30 Stephen J. Fey CelVivo ApS, Denmark
Culture Conditions Matter
10:30 – 10:45 Fabienne Dumoulin Acıbadem Mehmet Ali Aydınlar University, Turkey
Photodynamic therapy – Are light-triggered oxidative damages the magic solution to AMR?
10:45 – 11:15 Coffee break
Session 5 | Chairman: PRIYANKA SAHARIAH (Iceland)
11:15 – 11:30 Younes Smani University of Pablo de Olavide, Spain
Innovative antimicrobial strategy for the treatment of MDR bacterial infection
11:30 – 11:45 Bengt Erik Haug University of Bergen, Norway
Novel ligands for the flavin mononucleotide riboswitch
11:45 – 12:00 Bruno L. Victor University of Lisbon, Portugal
How can the Structure-based Molecular Modeling group from FCUL boost the EURESTOP
12:00 – 12:15 Kaja Kasemets National Institute of Chemical Physics and Biophysics, Estonia
Antimicrobial chitosan-nanocomposites for biomedical applications
12:15 – 12:30 Maria M. M. Santos University of Lisbon, Portugal
Spirooxindoles for targeting cancer and malaria. Perspectives of antibacterial activity
12:30 – 12:45 Giorgia Giovannini Swiss Federal Laboratories for Materials Science & Technology, Switzerland
Diagnosis and treatment of bacterial infections
12:45 – 14:30 Lunch break
Session 6 | Chairman: YOUNES SMANI (Spain)
14:30 – 14:45 Rossella Grande University of Chieti-Pescara, Italy
Antimicrobial and Antibiofilm Activities of Carvacrol and Thymol: Effective Carbonic Anhydrase Inhibitors versus Helicobacter pylori
14:45 – 15:00 Gabrielle Bangay Universidade Lusófona, Portugal
Chemical design of halimane diterpene for enhanced antimicrobial activity
15:00 – 15:15 Ryszard Ostaszewski Institute of Organic Chemistry, Poland
Application of multicomponent reactions for the synthesis of a new potential antimicrobial drugs
15:15 – 15:30 Ivana Kovačević University of Novi Sad, Serbia
Natural products with γ-butyrolactone moiety as potential antibiotics
15:30 – 15:45 Sanja Glisic Institute of Nuclear Sciences VINCA, Serbia
Efficient in silico approach for selection therapeutics against DR bacteria and identification of new therapeutic targets
15:45 – 16:00 Entela Haloci University of Medicine, Albania
A comparative study of antibacterial and antifungal activities of some essential oils
16:00 – 16:30 Coffee break
Session 7 | Chairman: TOMISLAV MESTROVIC (Croatia)
16:30 – 16:45 Nace Zidar University of Ljubljana, Slovenia
Discovery of new inhibitors of DNA gyrase and topoisomerase IV to overcome antimicrobial resistance
16:45 – 17:00 Paulo J. Costa University of Lisbon, Portugal
Studying molecular recognition phenomena using computational tools: the case of halogenated drugs
17:00 – 17:15 Jitka Viktorova University of Chemistry and Technology Prague, Czech Republic
Antibiotic resistance platform for high-throughput screening of adjuvants for combination therapies
17:15 – 17:30 Carole Devaux Luxembourg Institute of Health, Luxembourg
Development of immunotherapeutic complexes eliciting complement activation towards multidrug- resistant Pseudomonas aeruginosa
17:30 – 17:40 – CA21145 Organizing Committee
Closing remarks, next meetings and activities
Meals Information
Download the pdf of Meeting Program
